Welcome to our website!

Product Catalog

Rapid Product Index

Recommended Products

Friend Links

  • Rivaroxaban
Name:Rivaroxaban
CAS No:366789-02-8

PRODUCT DESCRIPTION

【Name】

2-Thiophenecarboxamide,5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-

Rivaroxaban

【Iupac name】
5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,
3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
【CAS Registry number】
366789-02-8
【Synonyms】
5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide
BAY 59-7939
Xarelto;
【Molecular Formula】
C19H18ClN3O5S (Products with the same molecular formula)
【Molecular Weight】
435.8813
【Inchi】
InChI=1/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
【Canonical SMILES】
C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl
【Isomers smiles】
C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl
【MOL File】
366789-02-8.mol

Chemical and Physical Properties

【Density】
1.46g/cm3
【Boiling Point】
732.6°Cat760mmHg
【Refractive Index】
1.633
【Flash Point】
396.9°C
【Computed Properties】
Molecular Weight:435.88132 [g/mol]
Molecular Formula:C19H18ClN3O5S
XLogP3-AA:2.5
H-Bond Donor:1
H-Bond Acceptor:6
Rotatable Bond Count:5
Tautomer Count:4
Exact Mass:435.065569
MonoIsotopic Mass:435.065569
Topological Polar Surface Area:116
Heavy Atom Count:29
Formal Charge:0
Complexity:645
Isotope Atom Count:0
Defined Atom Stereocenter Count:1
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:4
Feature 3D Donor Count:1
Feature 3D Ring Count:4
Effective Rotor Count:7.8
Conformer Sampling RMSD:1
CID Conformer Count:55

Use and Manufacturing

【Usage】

A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor

Biomedical Effects and Toxicity

【Pharmacological Action】
- Agents that prevent clotting.

RELATED PRODUCTS