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  • chlorambucil  305-03-3
Name:chlorambucil 305-03-3
CAS No:305-03-3

PRODUCT DESCRIPTION

Description

Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Basic Info

Chemical Name chlorambucil
Synonyms

4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid;Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-;Chlorambucil;4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid 4-[Bis(2-chloroethyl)amino]benzenebutyric acid;

CAS No. 305-03-3
Molecular Formula C14H19Cl2NO2
Molecular Weight 304.21200
PSA 40.54000
LogP 3.37790

Numbering system

UNII 18D0SL7309

Properties

Appearance & Physical State beige powder
Density 1.248 g/cm3
Boiling Point 460.1ºC at 760 mmHg
Melting Point 64ºC
Flash Point 232.1ºC
Refractive Index 1.536
Stability Stable, but may be light sensitive. Store cold. Incompatible with strong oxidizing agents.
Storage Condition 2-8ºC

Safety Info

RTECS ES7525000
Hazard Class 6.1(b)
Safety Statements S53-S26-S45
HS Code 2922499990
Packing Group III
WGK Germany 3
RIDADR UN 2811
Risk Statements R45; R25; R36/37/38
Hazard Codes T
Hazard Declaration H301; H315; H319; H335; H350
Caution Statement P201; P261; P301 + P310; P305 + P351 + P338; P308 + P313
Signal Word Danger
Symbol GHS06, GHS08

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